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Subthreshold α (2)-Adrenergic Activation Counteracts Glucagon-Like Peptide-1 Potentiation of Glucose-Stimulated Insulin Secretion

The pancreatic β cell harbors α (2)-adrenergic and glucagon-like peptide-1 (GLP-1) receptors on its plasma membrane to sense the corresponding ligands adrenaline/noradrenaline and GLP-1 to govern glucose-stimulated insulin secretion. However, it is not known whether these two signaling systems inter...

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Detalles Bibliográficos
Autores principales: Pan, Minglin, Yang, Guang, Cui, Xiuli, Yang, Shao-Nian
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3021849/
https://www.ncbi.nlm.nih.gov/pubmed/21253359
http://dx.doi.org/10.1155/2011/604989