Reverse Genetics Modification of Cytomegalovirus Antigenicity and Immunogenicity by CD8 T-Cell Epitope Deletion and Insertion

The advent of cloning herpesviral genomes as bacterial artificial chromosomes (BACs) has made herpesviruses accessible to bacterial genetics and has thus revolutionised their mutagenesis. This opened all possibilities of reverse genetics to ask scientific questions by introducing precisely accurate...

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Detalles Bibliográficos
Autores principales: Lemmermann, Niels A. W., Kropp, Kai A., Seckert, Christof K., Grzimek, Natascha K. A., Reddehase, Matthias J.
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2011
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3021883/
https://www.ncbi.nlm.nih.gov/pubmed/21253509
http://dx.doi.org/10.1155/2011/812742

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3021883/
https://www.ncbi.nlm.nih.gov/pubmed/21253509
http://dx.doi.org/10.1155/2011/812742

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