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Identification of Candidate Tumour Suppressor Genes Frequently Methylated in Renal Cell Carcinoma

Promoter region hyermethylation and transcriptional silencing is a frequent cause of tumour suppressor gene (TSG) inactivation in many types of human cancers. Functional epigenetic studies, in which gene expression is induced by treatment with demethylating agents, may identify novel genes with tumo...

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Detalles Bibliográficos
Autores principales: Morris, Mark R., Ricketts, Christopher, Gentle, Dean, Abdulrahman, Mahera, Clarke, Noel, Brown, Michael, Kishida, Takeshi, Yao, Masahiro, Latif, Farida, Maher, Eamonn R
Formato: Texto
Lenguaje:English
Publicado: 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3021900/
https://www.ncbi.nlm.nih.gov/pubmed/20154727
http://dx.doi.org/10.1038/onc.2009.493