Cargando…

Epithelial Hic-5/ARA55 expression contributes to prostate tumorigenesis and castrate responsiveness

Stromal–epithelial interactions dictate prostate tumorigenesis and response to castration. Hydrogen peroxide-inducible clone 5 (Hic-5/ARA55) is a transforming growth factor-beta (TGF-β)-induced coactivator of androgen receptor (AR) expressed in the prostate stroma. Interestingly, following castratio...

Descripción completa

Detalles Bibliográficos
Autores principales: Li, X, Martinez-Ferrer, M, Botta, V, Uwamariya, C, Banerjee, J, Bhowmick, N A
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3021901/
https://www.ncbi.nlm.nih.gov/pubmed/20818421
http://dx.doi.org/10.1038/onc.2010.400