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Mitochondrial Function Is Required for Secretion of DAF-28/Insulin in C. elegans

While insulin signaling has been extensively studied in Caenorhabditis elegans in the context of ageing and stress response, less is known about the factors underlying the secretion of insulin ligands upstream of the insulin receptor. Activation of the receptor governs the decision whether to progre...

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Detalles Bibliográficos
Autores principales: Billing, Ola, Kao, Gautam, Naredi, Peter
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3022011/
https://www.ncbi.nlm.nih.gov/pubmed/21264209
http://dx.doi.org/10.1371/journal.pone.0014507