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Identification of Distinctive Patterns of USP19-Mediated Growth Regulation in Normal and Malignant Cells
We previously reported that the USP19 deubiquitinating enzyme positively regulates proliferation in fibroblasts by stabilizing KPC1, a ubiquitin ligase for p27(Kip1). To explore whether this role of USP19 extends to other cellular systems, we tested the effects of silencing of USP19 in several human...
| Autores principales: | , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2011
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3022023/ https://www.ncbi.nlm.nih.gov/pubmed/21264218 http://dx.doi.org/10.1371/journal.pone.0015936 |