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Nucleotides function as endogenous chemical sensors for oxidative stress signaling

Oxidized and nitrated nucleotides including 8-oxogunanine and 8-nitroguanine derivatives such as 8-nitroguanosine 3',5'-cyclic monophosphate were generated by reactive nitrogen oxides and reactive oxygen species in cultured cells and in tissues. 8-oxoguanine and 8-nitroguanine in DNA and R...

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Detalles Bibliográficos
Autores principales: Ihara, Hideshi, Sawa, Tomohiro, Nakabeppu, Yusaku, Akaike, Takaaki
Formato: Texto
Lenguaje:English
Publicado: the Society for Free Radical Research Japan 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3022061/
https://www.ncbi.nlm.nih.gov/pubmed/21297909
http://dx.doi.org/10.3164/jcbn.11-003FR