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The optimal concentration of siRNA for gene silencing in primary cultured astrocytes and microglial cells of rats

BACKGROUND: Small interfering RNAs (siRNAs) have been used to knockdown specific gene expression in various cells. Astrocytes and microglial cells play a key role in fundamental central nervous system functions and in chronic neuroinflammation. The aims of this study were to determine the optimal co...

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Detalles Bibliográficos
Autores principales: Ki, Kyeong Ho, Park, Do Yang, Lee, Soo Han, Kim, Nam Yun, Choi, Byung Moon, Noh, Gyu Jeong
Formato: Texto
Lenguaje:English
Publicado: The Korean Society of Anesthesiologists 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3022134/
https://www.ncbi.nlm.nih.gov/pubmed/21253378
http://dx.doi.org/10.4097/kjae.2010.59.6.403