Down-regulation of endothelial TLR4 signalling after apo A-I gene transfer contributes to improved survival in an experimental model of lipopolysaccharide-induced inflammation

The protective effects of high-density lipoprotein (HDL) under lipopolysaccharide (LPS) conditions have been well documented. Here, we investigated whether an effect of HDL on Toll-like receptor 4 (TLR4) expression and signalling may contribute to its endothelial-protective effects and to improved s...

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Detalles Bibliográficos
Autores principales: Van Linthout, Sophie, Spillmann, Frank, Graiani, Gallia, Miteva, Kapka, Peng, Jun, Van Craeyveld, Eline, Meloni, Marco, Tölle, Markus, Escher, Felicitas, Subasigüller, Aysun, Doehner, Wolfram, Quaini, Federico, De Geest, Bart, Schultheiss, Heinz-Peter, Tschöpe, Carsten
Formato: Texto
Lenguaje:English
Publicado: Springer-Verlag 2010
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3022151/
https://www.ncbi.nlm.nih.gov/pubmed/20972769
http://dx.doi.org/10.1007/s00109-010-0690-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3022151/
https://www.ncbi.nlm.nih.gov/pubmed/20972769
http://dx.doi.org/10.1007/s00109-010-0690-6

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