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Down-regulation of endothelial TLR4 signalling after apo A-I gene transfer contributes to improved survival in an experimental model of lipopolysaccharide-induced inflammation
The protective effects of high-density lipoprotein (HDL) under lipopolysaccharide (LPS) conditions have been well documented. Here, we investigated whether an effect of HDL on Toll-like receptor 4 (TLR4) expression and signalling may contribute to its endothelial-protective effects and to improved s...
Autores principales: | Van Linthout, Sophie, Spillmann, Frank, Graiani, Gallia, Miteva, Kapka, Peng, Jun, Van Craeyveld, Eline, Meloni, Marco, Tölle, Markus, Escher, Felicitas, Subasigüller, Aysun, Doehner, Wolfram, Quaini, Federico, De Geest, Bart, Schultheiss, Heinz-Peter, Tschöpe, Carsten |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Springer-Verlag
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3022151/ https://www.ncbi.nlm.nih.gov/pubmed/20972769 http://dx.doi.org/10.1007/s00109-010-0690-6 |
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