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Variation in amount of wild-type transthyretin in different fibril and tissue types in ATTR amyloidosis

Familial transthyretin (TTR) amyloidosis is caused by a mutation in the TTR gene, although wild-type (wt) TTR is also incorporated into the amyloid fibrils. Liver transplantation (LT) is the prevailing treatment of the disease and is performed in order to eliminate the mutant TTR from plasma. The ou...

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Detalles Bibliográficos
Autores principales: Ihse, Elisabet, Suhr, Ole B., Hellman, Ulf, Westermark, Per
Formato: Texto
Lenguaje:English
Publicado: Springer-Verlag 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3022153/
https://www.ncbi.nlm.nih.gov/pubmed/21107516
http://dx.doi.org/10.1007/s00109-010-0695-1