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Choline Modulation of the Aβ P1-40 Channel Reconstituted into a Model Lipid Membrane

Nicotinic acetylcholine receptors (AChRs), implicated in memory and learning, in subjects affected by Alzheimer's disease result altered. Stimulation of α7-nAChRs inhibits amyloid plaques and increases ACh release. β-amyloid peptide (AβP) forms ion channels in the cell and model phospholipid me...

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Detalles Bibliográficos
Autores principales: Meleleo, Daniela, Notarachille, Gabriella, Micelli, Silvia
Formato: Texto
Lenguaje:English
Publicado: SAGE-Hindawi Access to Research 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3022179/
https://www.ncbi.nlm.nih.gov/pubmed/21253469
http://dx.doi.org/10.4061/2010/752804