Mammalian Models of Duchenne Muscular Dystrophy: Pathological Characteristics and Therapeutic Applications

Duchenne muscular dystrophy (DMD) is a devastating X-linked muscle disorder characterized by muscle wasting which is caused by mutations in the DMD gene. The DMD gene encodes the sarcolemmal protein dystrophin, and loss of dystrophin causes muscle degeneration and necrosis. Thus far, therapies for t...

Descripción completa

Detalles Bibliográficos
Autores principales: Nakamura, Akinori, Takeda, Shin'ichi
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2011
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3022202/
https://www.ncbi.nlm.nih.gov/pubmed/21274260
http://dx.doi.org/10.1155/2011/184393

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3022202/
https://www.ncbi.nlm.nih.gov/pubmed/21274260
http://dx.doi.org/10.1155/2011/184393

Ejemplares similares