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Mammalian Models of Duchenne Muscular Dystrophy: Pathological Characteristics and Therapeutic Applications
Duchenne muscular dystrophy (DMD) is a devastating X-linked muscle disorder characterized by muscle wasting which is caused by mutations in the DMD gene. The DMD gene encodes the sarcolemmal protein dystrophin, and loss of dystrophin causes muscle degeneration and necrosis. Thus far, therapies for t...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
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Hindawi Publishing Corporation
2011
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3022202/ https://www.ncbi.nlm.nih.gov/pubmed/21274260 http://dx.doi.org/10.1155/2011/184393 |