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Intravenous Sphingosylphosphorylcholine Protects Ischemic and Postischemic Myocardial Tissue in a Mouse Model of Myocardial Ischemia/Reperfusion Injury

HDL, through sphingosine-1-phosphate (S1P), exerts direct cardioprotective effects on ischemic myocardium. It remains unclear whether other HDL-associated sphingophospholipids have similar effects. We therefore examined if HDL-associated sphingosylphosphorylcholine (SPC) reduces infarct size in a mo...

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Detalles Bibliográficos
Autores principales: Herzog, Christine, Schmitz, Martina, Levkau, Bodo, Herrgott, Ilka, Mersmann, Jan, Larmann, Jan, Johanning, Kai, Winterhalter, Michael, Chun, Jerold, Müller, Frank Ulrich, Echtermeyer, Frank, Hildebrand, Reinhard, Theilmeier, Gregor
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3022218/
https://www.ncbi.nlm.nih.gov/pubmed/21274265
http://dx.doi.org/10.1155/2010/425191