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Rodent Preclinical Models for Developing Novel Antiarthritic Molecules: Comparative Biology and Preferred Methods for Evaluating Efficacy

Rodent models of immune-mediated arthritis (RMIA) are the conventional approach to evaluating mechanisms of inflammatory joint disease and the comparative efficacy of antiarthritic agents. Rat adjuvant-induced (AIA), collagen-induced (CIA), and streptococcal cell wall-induced (SCW) arthritides are p...

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Detalles Bibliográficos
Autores principales: Bolon, Brad, Stolina, Marina, King, Caroline, Middleton, Scot, Gasser, Jill, Zack, Debra, Feige, Ulrich
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3022224/
https://www.ncbi.nlm.nih.gov/pubmed/21253435
http://dx.doi.org/10.1155/2011/569068