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SHIP deficiency causes Crohn's disease-like ileitis
BACKGROUND: Inflammatory bowel disease (IBD) can arise from genetic mutations that compromise intestinal epithelial cell integrity or immune regulation. SHIP has previously been shown to play a pivotal role in limiting the number of immunoregulatory cells and their function. AIM: To determine whethe...
Autores principales: | , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BMJ Group
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3022365/ https://www.ncbi.nlm.nih.gov/pubmed/20940287 http://dx.doi.org/10.1136/gut.2009.202283 |