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Complex interplay between β-catenin signalling and Notch effectors in intestinal tumorigenesis

AIMS: The activation of β-catenin signalling is a key step in intestinal tumorigenesis. Interplay between the β-catenin and Notch pathways during tumorigenesis has been reported, but the mechanisms involved and the role of Notch remain unclear. METHODS: Notch status was analysed by studying expressi...

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Detalles Bibliográficos
Autores principales: Peignon, Grégory, Durand, Aurélie, Cacheux, Wulfran, Ayrault, Olivier, Terris, Benoît, Laurent-Puig, Pierre, Shroyer, Noah F, Van Seuningen, Isabelle, Honjo, Tasuku, Perret, Christine, Romagnolo, Béatrice
Formato: Texto
Lenguaje:English
Publicado: BMJ Group 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3022366/
https://www.ncbi.nlm.nih.gov/pubmed/21205878
http://dx.doi.org/10.1136/gut.2009.204719