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SecM-Stalled Ribosomes Adopt an Altered Geometry at the Peptidyl Transferase Center
As nascent polypeptide chains are synthesized, they pass through a tunnel in the large ribosomal subunit. Interaction between specific nascent chains and the ribosomal tunnel is used to induce translational stalling for the regulation of gene expression. One well-characterized example is the Escheri...
Autores principales: | , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3022528/ https://www.ncbi.nlm.nih.gov/pubmed/21267063 http://dx.doi.org/10.1371/journal.pbio.1000581 |