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Combinatorial analysis and algorithms for quasispecies reconstruction using next-generation sequencing

BACKGROUND: Next-generation sequencing (NGS) offers a unique opportunity for high-throughput genomics and has potential to replace Sanger sequencing in many fields, including de-novo sequencing, re-sequencing, meta-genomics, and characterisation of infectious pathogens, such as viral quasispecies. A...

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Detalles Bibliográficos
Autores principales: Prosperi, Mattia CF, Prosperi, Luciano, Bruselles, Alessandro, Abbate, Isabella, Rozera, Gabriella, Vincenti, Donatella, Solmone, Maria Carmela, Capobianchi, Maria Rosaria, Ulivi, Giovanni
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3022557/
https://www.ncbi.nlm.nih.gov/pubmed/21208435
http://dx.doi.org/10.1186/1471-2105-12-5