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Pyronaridine-Artesunate versus Chloroquine in Patients with Acute Plasmodium vivax Malaria: A Randomized, Double-Blind, Non-Inferiority Trial

BACKGROUND: New antimalarials are needed for P. vivax and P. falciparum malaria. This study compared the efficacy and safety of pyronaridine-artesunate with that of chloroquine for the treatment of uncomplicated P. vivax malaria. METHODS AND FINDINGS: This phase III randomized, double-blind, non-inf...

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Detalles Bibliográficos
Autores principales: Poravuth, Yi, Socheat, Duong, Rueangweerayut, Ronnatrai, Uthaisin, Chirapong, Pyae Phyo, Aung, Valecha, Neena, Rao, B. H. Krishnamoorthy, Tjitra, Emiliana, Purnama, Asep, Borghini-Fuhrer, Isabelle, Duparc, Stephan, Shin, Chang-Sik, Fleckenstein, Lawrence
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3022577/
https://www.ncbi.nlm.nih.gov/pubmed/21267072
http://dx.doi.org/10.1371/journal.pone.0014501