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DNA Methylation of the First Exon Is Tightly Linked to Transcriptional Silencing
Tissue specific patterns of methylated cytosine residues vary with age, can be altered by environmental factors, and are often abnormal in human disease yet the cellular consequences of DNA methylation are incompletely understood. Although the bodies of highly expressed genes are often extensively m...
Autores principales: | , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3022582/ https://www.ncbi.nlm.nih.gov/pubmed/21267076 http://dx.doi.org/10.1371/journal.pone.0014524 |