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The Physiological Link between Metabolic Rate Depression and Tau Phosphorylation in Mammalian Hibernation

Abnormal phosphorylation and aggregation of tau protein are hallmarks of a variety of neurological disorders, including Alzheimer's disease (AD). Increased tau phosphorylation is assumed to represent an early event in pathogenesis and a pivotal aspect for aggregation and formation of neurofibri...

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Detalles Bibliográficos
Autores principales: Stieler, Jens T., Bullmann, Torsten, Kohl, Franziska, Tøien, Øivind, Brückner, Martina K., Härtig, Wolfgang, Barnes, Brian M., Arendt, Thomas
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3022585/
https://www.ncbi.nlm.nih.gov/pubmed/21267079
http://dx.doi.org/10.1371/journal.pone.0014530