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The Physiological Link between Metabolic Rate Depression and Tau Phosphorylation in Mammalian Hibernation
Abnormal phosphorylation and aggregation of tau protein are hallmarks of a variety of neurological disorders, including Alzheimer's disease (AD). Increased tau phosphorylation is assumed to represent an early event in pathogenesis and a pivotal aspect for aggregation and formation of neurofibri...
| Autores principales: | , , , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2011
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3022585/ https://www.ncbi.nlm.nih.gov/pubmed/21267079 http://dx.doi.org/10.1371/journal.pone.0014530 |