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Generation and characterization of high affinity human monoclonal antibodies that neutralize staphylococcal enterotoxin B

BACKGROUND: Staphylococcal enterotoxins are considered potential biowarfare agents that can be spread through ingestion or inhalation. Staphylococcal enterotoxin B (SEB) is a widely studied superantigen that can directly stimulate T-cells to release a massive amount of proinflammatory cytokines by b...

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Detalles Bibliográficos
Autores principales: Drozdowski, Brian, Zhou, Yuhong, Kline, Brad, Spidel, Jared, Chan, Yin Yin, Albone, Earl, Turchin, Howard, Chao, Qimin, Henry, Marianne, Balogach, Jacqueline, Routhier, Eric, Bavari, Sina, Nicolaides, Nicholas C, Sass, Philip M, Grasso, Luigi
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3022601/
https://www.ncbi.nlm.nih.gov/pubmed/21176153
http://dx.doi.org/10.1186/1476-8518-8-9