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Hepcidin induces HIV-1 transcription inhibited by ferroportin

BACKGROUND: Physiological regulation of cellular iron involves iron export by the membrane protein, ferroportin, the expression of which is induced by iron and negatively modulated by hepcidin. We previously showed that iron chelation is associated with decreased HIV-1 transcription. We hypothesized...

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Detalles Bibliográficos
Autores principales: Xu, Min, Kashanchi, Fatah, Foster, Altreisha, Rotimi, Jamie, Turner, Willie, Gordeuk, Victor R, Nekhai, Sergei
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3022686/
https://www.ncbi.nlm.nih.gov/pubmed/21126372
http://dx.doi.org/10.1186/1742-4690-7-104