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Hepcidin induces HIV-1 transcription inhibited by ferroportin
BACKGROUND: Physiological regulation of cellular iron involves iron export by the membrane protein, ferroportin, the expression of which is induced by iron and negatively modulated by hepcidin. We previously showed that iron chelation is associated with decreased HIV-1 transcription. We hypothesized...
Autores principales: | Xu, Min, Kashanchi, Fatah, Foster, Altreisha, Rotimi, Jamie, Turner, Willie, Gordeuk, Victor R, Nekhai, Sergei |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3022686/ https://www.ncbi.nlm.nih.gov/pubmed/21126372 http://dx.doi.org/10.1186/1742-4690-7-104 |
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