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Lack of α8 integrin leads to morphological changes in renal mesangial cells, but not in vascular smooth muscle cells

BACKGROUND: Extracellular matrix receptors of the integrin family are known to regulate cell adhesion, shape and functions. The α8 integrin chain is expressed in glomerular mesangial cells and in vascular smooth muscle cells. Mice deficient for α8 integrin have structural alterations in glomeruli bu...

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Detalles Bibliográficos
Autores principales: Marek, Ines, Volkert, Gudrun, Jahn, Angelika, Fahlbusch, Fabian, Zürn, Christina, Özcan, Zehra, Goppelt-Struebe, Margarete, Hilgers, Karl F, Rascher, Wolfgang, Hartner, Andrea
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3022721/
https://www.ncbi.nlm.nih.gov/pubmed/21194485
http://dx.doi.org/10.1186/1471-2121-11-102