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Plasmacytoid dendritic cells are increased in cerebrospinal fluid of untreated patients during multiple sclerosis relapse

The plasmacytoid dendritic cells (pDCs) express a high level of Toll-like receptor 9 (TLR-9), which recognizes viral DNA. Activated via TLR-9, pDCs also secrete large amounts of type I interferon which are involved either in stimulation or down regulation of immune response in multiple sclerosis (MS...

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Detalles Bibliográficos
Autores principales: Longhini, Ana Leda F, von Glehn, Felipe, Brandão, Carlos Otávio, de Paula, Rosemeire FO, Pradella, Fernando, Moraes, Adriel S, Farias, Alessandro S, Oliveira, Elaine C, Quispe-Cabanillas, Juan G, Abreu, Cassiana Horta, Damasceno, Alfredo, Damasceno, Benito P, Balashov, Konstantin E, Santos, Leonilda MB
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3022734/
https://www.ncbi.nlm.nih.gov/pubmed/21214939
http://dx.doi.org/10.1186/1742-2094-8-2