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TPL2/COT/MAP3K8 (TPL2) Activation Promotes Androgen Depletion-Independent (ADI) Prostate Cancer Growth

BACKGROUND: Despite its initial positive response to hormone ablation therapy, prostate cancers invariably recur in more aggressive, treatment resistant forms. The lack of our understanding of underlying genetic alterations for the transition from androgen-dependent (AD) to ADI prostate cancer growt...

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Detalles Bibliográficos
Autores principales: Jeong, Joseph H., Bhatia, Ayesha, Toth, Zsolt, Oh, Soohwan, Inn, Kyung-Soo, Liao, Chun-Peng, Roy-Burman, Pradip, Melamed, Jonathan, Coetzee, Gerhard A., Jung, Jae U.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3022761/
https://www.ncbi.nlm.nih.gov/pubmed/21267413
http://dx.doi.org/10.1371/journal.pone.0016205