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The minor C-allele of rs2014355 in ACADS is associated with reduced insulin release following an oral glucose load

BACKGROUND: A genome-wide association study (GWAS) using metabolite concentrations as proxies for enzymatic activity, suggested that two variants: rs2014355 in the gene encoding short-chain acyl-coenzyme A dehydrogenase (ACADS) and rs11161510 in the gene encoding medium-chain acyl-coenzyme A dehydro...

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Detalles Bibliográficos
Autores principales: Hornbak, Malene, Banasik, Karina, Justesen, Johanne M, Krarup, Nikolaj T, Sandholt, Camilla H, Andersson, Åsa, Sandbæk, Annelli, Lauritzen, Torsten, Pisinger, Charlotta, Witte, Daniel R, Sørensen, Thorkild IA, Pedersen, Oluf, Hansen, Torben
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3022800/
https://www.ncbi.nlm.nih.gov/pubmed/21211036
http://dx.doi.org/10.1186/1471-2350-12-4