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Structural and functional characterization of human apolipoprotein E 72-166 peptides in both aqueous and lipid environments
BACKGROUNDS: There are three apolipoprotein E (apoE) isoforms involved in human lipid homeostasis. In the present study, truncated apoE2-, apoE3- and apoE4-(72-166) peptides that are tailored to lack domain interactions are expressed and elucidated the structural and functional consequences. METHODS...
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Formato: | Texto |
Lenguaje: | English |
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BioMed Central
2011
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3022805/ https://www.ncbi.nlm.nih.gov/pubmed/21219628 http://dx.doi.org/10.1186/1423-0127-18-4 |