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Structural and functional characterization of human apolipoprotein E 72-166 peptides in both aqueous and lipid environments

BACKGROUNDS: There are three apolipoprotein E (apoE) isoforms involved in human lipid homeostasis. In the present study, truncated apoE2-, apoE3- and apoE4-(72-166) peptides that are tailored to lack domain interactions are expressed and elucidated the structural and functional consequences. METHODS...

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Detalles Bibliográficos
Autores principales: Hsieh, Yi-Hui, Chou, Chi-Yuan
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3022805/
https://www.ncbi.nlm.nih.gov/pubmed/21219628
http://dx.doi.org/10.1186/1423-0127-18-4

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