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APP processing in Alzheimer's disease

An important pathological feature of Alzheimer's disease (AD) is the presence of extracellular senile plaques in the brain. Senile plaques are composed of aggregations of small peptides called β-amyloid (Aβ). Multiple lines of evidence demonstrate that overproduction/aggregation of Aβ in the br...

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Detalles Bibliográficos
Autores principales: Zhang, Yun-wu, Thompson, Robert, Zhang, Han, Xu, Huaxi
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3022812/
https://www.ncbi.nlm.nih.gov/pubmed/21214928
http://dx.doi.org/10.1186/1756-6606-4-3