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The SOX2 response program in glioblastoma multiforme: an integrated ChIP-seq, expression microarray, and microRNA analysis

BACKGROUND: SOX2 is a key gene implicated in maintaining the stemness of embryonic and adult stem cells. SOX2 appears to re-activate in several human cancers including glioblastoma multiforme (GBM), however, the detailed response program of SOX2 in GBM has not yet been defined. RESULTS: We show that...

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Detalles Bibliográficos
Autores principales: Fang, Xuefeng, Yoon, Jae-Geun, Li, Lisha, Yu, Wei, Shao, Jiaofang, Hua, Dasong, Zheng, Shu, Hood, Leroy, Goodlett, David R, Foltz, Gregory, Lin, Biaoyang
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3022822/
https://www.ncbi.nlm.nih.gov/pubmed/21211035
http://dx.doi.org/10.1186/1471-2164-12-11