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Cyclophilin A is an inflammatory mediator that promotes atherosclerosis in apolipoprotein E–deficient mice

Cyclophilin A (CyPA; encoded by Ppia) is a ubiquitously expressed protein secreted in response to inflammatory stimuli. CyPA stimulates vascular smooth muscle cell migration and proliferation, endothelial cell adhesion molecule expression, and inflammatory cell chemotaxis. Given these activities, we...

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Detalles Bibliográficos
Autores principales: Nigro, Patrizia, Satoh, Kimio, O'Dell, Michael R., Soe, Nwe Nwe, Cui, Zhaoqiang, Mohan, Amy, Abe, Jun-ichi, Alexis, Jeffrey D., Sparks, Janet D., Berk, Bradford C.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3023134/
https://www.ncbi.nlm.nih.gov/pubmed/21173104
http://dx.doi.org/10.1084/jem.20101174