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Cyclophilin A is an inflammatory mediator that promotes atherosclerosis in apolipoprotein E–deficient mice
Cyclophilin A (CyPA; encoded by Ppia) is a ubiquitously expressed protein secreted in response to inflammatory stimuli. CyPA stimulates vascular smooth muscle cell migration and proliferation, endothelial cell adhesion molecule expression, and inflammatory cell chemotaxis. Given these activities, we...
Autores principales: | Nigro, Patrizia, Satoh, Kimio, O'Dell, Michael R., Soe, Nwe Nwe, Cui, Zhaoqiang, Mohan, Amy, Abe, Jun-ichi, Alexis, Jeffrey D., Sparks, Janet D., Berk, Bradford C. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3023134/ https://www.ncbi.nlm.nih.gov/pubmed/21173104 http://dx.doi.org/10.1084/jem.20101174 |
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