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Strain-specific activation of the NF-κB pathway by GRA15, a novel Toxoplasma gondii dense granule protein

NF-κB is an integral component of the immune response to Toxoplasma gondii. Although evidence exists that T. gondii can directly modulate the NF-κB pathway, the parasite-derived effectors involved are unknown. We determined that type II strains of T. gondii activate more NF-κB than type I or type II...

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Detalles Bibliográficos
Autores principales: Rosowski, Emily E., Lu, Diana, Julien, Lindsay, Rodda, Lauren, Gaiser, Rogier A., Jensen, Kirk D.C., Saeij, Jeroen P.J.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3023140/
https://www.ncbi.nlm.nih.gov/pubmed/21199955
http://dx.doi.org/10.1084/jem.20100717