Cargando…

Unsaturated FAs prevent palmitate-induced LOX-1 induction via inhibition of ER stress in macrophages

Palmitic acid (PA) upregulates oxidized LDL receptor-1 (LOX-1), a scavenger receptor responsible for uptake of oxidized LDL (oxLDL), and enhances oxLDL uptake in macrophages. However, the precise underlying mechanism remains to be elucidated. PA is known to induce endoplasmic reticulum (ER) stress i...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ishiyama, Junichi, Taguchi, Ryoko, Akasaka, Yunike, Shibata, Saiko, Ito, Minoru, Nagasawa, Michiaki, Murakami, Koji
Formato:	Texto
Lenguaje:	English
Publicado:	The American Society for Biochemistry and Molecular Biology 2011
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3023550/ https://www.ncbi.nlm.nih.gov/pubmed/21078775 http://dx.doi.org/10.1194/jlr.M007104

Ejemplares similares

Secreted protein acidic and rich in cysteine (SPARC) is upregulated by transforming growth factor (TGF)-β and is required for TGF-β-induced hydrogen peroxide production in fibroblasts
por: Shibata, Saiko, et al.
Publicado: (2013)

Activation of AMP-activated protein kinase (AMPK) through inhibiting interaction with prohibitins
por: Kanagaki, Shuhei, et al.
Publicado: (2023)

Palmitic Acid Lipotoxicity in Microglia Cells Is Ameliorated by Unsaturated Fatty Acids
por: Urso, C.J., et al.
Publicado: (2021)

Potential options for managing LOX+ ER− breast cancer patients
por: Han, Yong, et al.
Publicado: (2016)

Curcumin Alleviates Palmitic Acid-Induced LOX-1 Upregulation by Suppressing Endoplasmic Reticulum Stress in HUVECs
por: Luo, Ruixi, et al.
Publicado: (2021)

Palmitate reduces starvation-induced ER stress by inhibiting ER-phagy in hypothalamic cells
por: Lim, Yun, et al.
Publicado: (2021)

Investigating the experiences of family caregivers who shackle people with mental disorders
por: Kusumawaty, Ira, et al.
Publicado: (2023)

Palmitic and linoleic acids induce ER stress and apoptosis in hepatoma cells
por: Zhang, Yong, et al.
Publicado: (2012)

Resveratrol Enhances Palmitate-Induced ER Stress and Apoptosis in Cancer Cells
por: Rojas, Cristina, et al.
Publicado: (2014)

Differential Induction of Apoptosis by Fas–Fas Ligand Interactions in Human Monocytes and Macrophages
por: Kiener, Peter A., et al.
Publicado: (1997)

The role of lipid droplet formation in the protection of unsaturated fatty acids against palmitic acid induced lipotoxicity to rat insulin-producing cells
por: Plötz, Thomas, et al.
Publicado: (2016)

Replacing the wild type loxP site in BACs from the public domain with lox66 using a lox66 transposon
por: Chatterjee, Pradeep K, et al.
Publicado: (2010)

New Mouse Lines for the Analysis of Neuronal Morphology Using CreER(T)/loxP-Directed Sparse Labeling
por: Badea, Tudor C., et al.
Publicado: (2009)

Oncolytic Poxvirus Armed with Fas Ligand Leads to Induction of Cellular Fas Receptor and Selective Viral Replication in FasR Negative Cancer
por: Sathaiah, Magesh, et al.
Publicado: (2011)

DNA damage promotes ER stress resistance through elevation of unsaturated phosphatidylcholine in Caenorhabditis elegans
por: Deng, Jianhui, et al.
Publicado: (2020)

ER calcium release promotes mitochondrial dysfunction and hepatic cell lipotoxicity in response to palmitate overload
por: Egnatchik, Robert A., et al.
Publicado: (2014)

Palmitate induces ER calcium depletion and apoptosis in mouse podocytes subsequent to mitochondrial oxidative stress
por: Xu, S, et al.
Publicado: (2015)

Oleic acid ameliorates palmitic acid induced hepatocellular lipotoxicity by inhibition of ER stress and pyroptosis
por: Zeng, Xin, et al.
Publicado: (2020)

The extracellular domains of FasL and Fas are sufficient for the formation of supramolecular FasL-Fas clusters of high stability
por: Henkler, Frank, et al.
Publicado: (2005)

The status of Fas and Fas ligand expression can predict recurrence of hepatocellular carcinoma
por: Ito, Y, et al.
Publicado: (2000)

LOX-1 boosts immunity
por: Oh, SangKon, et al.
Publicado: (2015)

LOX-1 in Ischemic Stroke
por: Sawamura, Tatsuya, et al.
Publicado: (2017)

Lox’d in translation: contradictions in the nomenclature surrounding common lox-site mutants and their implications in experiments
por: Shaw, Daniel, et al.
Publicado: (2020)

Identification of the LOX Gene Family in Peanut and Functional Characterization of AhLOX29 in Drought Tolerance
por: Mou, Yifei, et al.
Publicado: (2022)

Manic Symptoms during a Switch from Paliperidone ER to Paliperidone Palmitate in a Patient with Schizophrenia
por: Demirci, Kadir, et al.
Publicado: (2015)

Correction to: Oleic acid ameliorates palmitic acid induced hepatocellular lipotoxicity by inhibition of ER stress and pyroptosis
por: Zeng, Xin, et al.
Publicado: (2020)

5-ALA Attenuates the Palmitic Acid-Induced ER Stress and Apoptosis in Bovine Mammary Epithelial Cells
por: Sharmin, Mst Mamuna, et al.
Publicado: (2021)

Association of the LOX-1 rs1050283 Polymorphism with Risk for Atherosclerotic Cerebral Infarction and its Effect on sLOX-1 and LOX-1 Expression in a Chinese Population
por: Guo, Xin, et al.
Publicado: (2017)

The Fas counterattack: Fas-mediated T cell killing by colon cancer cells expressing Fas ligand
Publicado: (1996)

Associations of serum soluble Fas and Fas ligand (FasL) with outcomes in systemic lupus erythematosus
por: Vincent, Fabien B, et al.
Publicado: (2020)

The Role of Fas-FasL Signaling Pathway in Induction of Apoptosis in Patients with Sulfur Mustard-Induced Chronic Bronchiolitis
por: Pirzad, Gila, et al.
Publicado: (2010)

Characterization of Genetic Diversity and Linkage Disequilibrium of ZmLOX4 and ZmLOX5 Loci in Maize
por: De La Fuente, Gerald N., et al.
Publicado: (2013)

Improved scFv Anti-LOX-1 Binding Activity by Fusion with LOX-1-Binding Peptides
por: Hu, Wei, et al.
Publicado: (2017)

Utilizing the LoxP-Stop-LoxP System to Control Transgenic ABC-Transporter Expression In Vitro
por: Esobi, Ikechukwu, et al.
Publicado: (2022)

Understanding the role of Fas-Fas ligand system in bone
por: Marusic, Ana, et al.
Publicado: (2012)

Differential expressions of Fas and Fas ligand in human placenta.
por: Roh, Cheong-Rae, et al.
Publicado: (2002)

Soluble Fas and the −670 Polymorphism of Fas in Lupus Nephritis
por: Bollain-y-Goytia, Juan José, et al.
Publicado: (2014)

The Fas/FasL System in Reproduction: Survival and Apoptosis
por: Mor, Gil, et al.
Publicado: (2002)

Healthy hearts lay off LOX
por: Maxmen, Amy
Publicado: (2009)

LOX-1, OxLDL, and Atherosclerosis
por: Pirillo, Angela, et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_hc5jqv8bgb7881kmo2217f6bpp