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The physiological roles of vesicular GABA transporter during embryonic development: a study using knockout mice

BACKGROUND: The vesicular GABA transporter (VGAT) loads GABA and glycine from the neuronal cytoplasm into synaptic vesicles. To address functional importance of VGAT during embryonic development, we generated global VGAT knockout mice and analyzed them. RESULTS: VGAT knockouts at embryonic day (E) 1...

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Detalles Bibliográficos
Autores principales: Saito, Kenzi, Kakizaki, Toshikazu, Hayashi, Ryotaro, Nishimaru, Hiroshi, Furukawa, Tomonori, Nakazato, Yoichi, Takamori, Shigeo, Ebihara, Satoe, Uematsu, Masakazu, Mishina, Masayoshi, Miyazaki, Jun-ichi, Yokoyama, Minesuke, Konishi, Shiro, Inoue, Koichi, Fukuda, Atsuo, Fukumoto, Manabu, Nakamura, Kenji, Obata, Kunihiko, Yanagawa, Yuchio
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3023674/
https://www.ncbi.nlm.nih.gov/pubmed/21190592
http://dx.doi.org/10.1186/1756-6606-3-40