Cargando…
The physiological roles of vesicular GABA transporter during embryonic development: a study using knockout mice
BACKGROUND: The vesicular GABA transporter (VGAT) loads GABA and glycine from the neuronal cytoplasm into synaptic vesicles. To address functional importance of VGAT during embryonic development, we generated global VGAT knockout mice and analyzed them. RESULTS: VGAT knockouts at embryonic day (E) 1...
Autores principales: | Saito, Kenzi, Kakizaki, Toshikazu, Hayashi, Ryotaro, Nishimaru, Hiroshi, Furukawa, Tomonori, Nakazato, Yoichi, Takamori, Shigeo, Ebihara, Satoe, Uematsu, Masakazu, Mishina, Masayoshi, Miyazaki, Jun-ichi, Yokoyama, Minesuke, Konishi, Shiro, Inoue, Koichi, Fukuda, Atsuo, Fukumoto, Manabu, Nakamura, Kenji, Obata, Kunihiko, Yanagawa, Yuchio |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2010
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3023674/ https://www.ncbi.nlm.nih.gov/pubmed/21190592 http://dx.doi.org/10.1186/1756-6606-3-40 |
Ejemplares similares
-
Motor dysfunction in cerebellar Purkinje cell-specific vesicular GABA transporter knockout mice
por: Kayakabe, Mikiko, et al.
Publicado: (2014) -
Genetic Deficiency of GABA Differentially Regulates Respiratory and Non-Respiratory Motor Neuron Development
por: Fogarty, Matthew J., et al.
Publicado: (2013) -
Loss of Glutamate Decarboxylase 67 in Somatostatin-Expressing Neurons Leads to Anxiety-Like Behavior and Alteration in the Akt/GSK3β Signaling Pathway
por: Miyata, Shigeo, et al.
Publicado: (2019) -
A glycine transporter 2-Cre knock-in mouse line for glycinergic neuron-specific gene manipulation
por: Kakizaki, Toshikazu, et al.
Publicado: (2017) -
Development of lentiviral vectors for efficient glutamatergic-selective gene expression in cultured hippocampal neurons
por: Egashira, Yoshihiro, et al.
Publicado: (2018)