Temporal and Tissue Specific Regulation of RP-Associated Splicing Factor Genes PRPF3, PRPF31 and PRPC8—Implications in the Pathogenesis of RP

BACKGROUND: Genetic mutations in several ubiquitously expressed RNA splicing genes such as PRPF3, PRP31 and PRPC8, have been found to cause retina-specific diseases in humans. To understand this intriguing phenomenon, most studies have been focused on testing two major hypotheses. One hypothesis ass...

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Detalles Bibliográficos
Autores principales: Cao, Huibi, Wu, Jing, Lam, Simon, Duan, Rongqi, Newnham, Catherine, Molday, Robert S., Graziotto, John J., Pierce, Eric A., Hu, Jim
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3023711/
https://www.ncbi.nlm.nih.gov/pubmed/21283520
http://dx.doi.org/10.1371/journal.pone.0015860

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3023711/
https://www.ncbi.nlm.nih.gov/pubmed/21283520
http://dx.doi.org/10.1371/journal.pone.0015860

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