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Increased Inducible Nitric Oxide Synthase Expression in Organs Is Associated with a Higher Severity of H5N1 Influenza Virus Infection

BACKGROUND: The mechanisms of disease severity caused by H5N1 influenza virus infection remain somewhat unclear. Studies have indicated that a high viral load and an associated hyper inflammatory immune response are influential during the onset of infection. This dysregulated inflammatory response w...

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Detalles Bibliográficos
Autores principales: Burggraaf, Simon, Bingham, John, Payne, Jean, Kimpton, Wayne G., Lowenthal, John W., Bean, Andrew G. D.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3023712/
https://www.ncbi.nlm.nih.gov/pubmed/21283521
http://dx.doi.org/10.1371/journal.pone.0014561