Transient Alteration of Cellular Redox Buffering before Irradiation Triggers Apoptosis in Head and Neck Carcinoma Stem and Non-Stem Cells

BACKGROUND: Head and neck squamous cell carcinoma (HNSCC) is an aggressive and recurrent malignancy owing to intrinsic radioresistance and lack of induction of apoptosis. The major focus of this work was to design a transient glutathione depleting strategy during the course of irradiation of HNSCC i...

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Detalles Bibliográficos
Autores principales: Boivin, Anthony, Hanot, Maité, Malesys, Céline, Maalouf, Mira, Rousson, Robert, Rodriguez-Lafrasse, Claire, Ardail, Dominique
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3023721/
https://www.ncbi.nlm.nih.gov/pubmed/21283807
http://dx.doi.org/10.1371/journal.pone.0014558

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3023721/
https://www.ncbi.nlm.nih.gov/pubmed/21283807
http://dx.doi.org/10.1371/journal.pone.0014558

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