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Maturation of monocyte derived dendritic cells with OK432 boosts IL-12p70 secretion and conveys strong T-cell responses

BACKGROUND: Design of tumour specific immunotherapies using the patients' own dendritic cells (DC) is a fast advancing scientific field. The functional qualities of the DC generated in vitro are critical, and today's gold standard for maturation is a cytokine cocktail consisting of IL-1β,...

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Detalles Bibliográficos
Autores principales: Hovden, Arnt-Ove, Karlsen, Marie, Jonsson, Roland, Aarstad, Hans Jørgen, Appel, Silke
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3023782/
https://www.ncbi.nlm.nih.gov/pubmed/21208424
http://dx.doi.org/10.1186/1471-2172-12-2