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Stepwise Release of Biologically Active HMGB1 during HSV-2 Infection

BACKGROUND: High mobility group box 1 protein (HMGB1) is a major endogenous danger signal that triggers inflammation and immunity during septic and aseptic stresses. HMGB1 recently emerged as a key soluble factor in the pathogenesis of various infectious diseases, but nothing is known of its behavio...

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Detalles Bibliográficos
Autores principales: Borde, Chloé, Barnay-Verdier, Stéphanie, Gaillard, Claire, Hocini, Hakim, Maréchal, Vincent, Gozlan, Joël
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3023802/
https://www.ncbi.nlm.nih.gov/pubmed/21283827
http://dx.doi.org/10.1371/journal.pone.0016145