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Stepwise Release of Biologically Active HMGB1 during HSV-2 Infection
BACKGROUND: High mobility group box 1 protein (HMGB1) is a major endogenous danger signal that triggers inflammation and immunity during septic and aseptic stresses. HMGB1 recently emerged as a key soluble factor in the pathogenesis of various infectious diseases, but nothing is known of its behavio...
Autores principales: | , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3023802/ https://www.ncbi.nlm.nih.gov/pubmed/21283827 http://dx.doi.org/10.1371/journal.pone.0016145 |