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C2-O-sLe(X) Glycoproteins Are E-Selectin Ligands that Regulate Invasion of Human Colon and Hepatic Carcinoma Cells

Similar to mechanisms of recruitment of activated leukocytes to inflamed tissues, selectins mediate adhesion and extravasation of circulating cancer cells. Our objective was to determine whether sialyl Lewis X modified core 2 O-glycans (C2-O-sLe(X)) present on colon and hepatic carcinoma cells promo...

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Detalles Bibliográficos
Autores principales: St. Hill, Catherine A., Baharo-Hassan, Dahabo, Farooqui, Mariya
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3023807/
https://www.ncbi.nlm.nih.gov/pubmed/21283832
http://dx.doi.org/10.1371/journal.pone.0016281