Midkine as a factor to counteract the deposition of amyloid β-peptide plaques: in vitro analysis and examination in knockout mice

BACKGROUND: Midkine is a heparin-binding cytokine involved in cell survival and various inflammatory processes. Midkine accumulates in senile plaques of patients with Alzheimer's disease, while it counteracts the cytotoxic effects of amyloid β-peptide and inhibits its oligomerization. The prese...

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Detalles Bibliográficos
Autores principales: Muramatsu1, Hisako, Yokoi, Katsunori, Chen, Lan, Ichihara-Tanaka, Keiko, Kimura, Terutoshi, Muramatsu, Takashi
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3024247/
https://www.ncbi.nlm.nih.gov/pubmed/21223602
http://dx.doi.org/10.1186/1755-7682-4-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3024247/
https://www.ncbi.nlm.nih.gov/pubmed/21223602
http://dx.doi.org/10.1186/1755-7682-4-1

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