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Downregulation of miR-342 is associated with tamoxifen resistant breast tumors

BACKGROUND: Tumor resistance to the selective estrogen receptor modulator tamoxifen remains a serious clinical problem especially in patients with tumors that also overexpress HER2. We have recently demonstrated that the clinically important isoform of HER2, HERΔ16, promotes therapeutically refracto...

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Detalles Bibliográficos
Autores principales: Cittelly, Diana M, Das, Partha M, Spoelstra, Nicole S, Edgerton, Susan M, Richer, Jennifer K, Thor, Ann D, Jones, Frank E
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3024251/
https://www.ncbi.nlm.nih.gov/pubmed/21172025
http://dx.doi.org/10.1186/1476-4598-9-317