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Global Analysis of the Impact of Environmental Perturbation on cis-Regulation of Gene Expression

Genetic variants altering cis-regulation of normal gene expression (cis-eQTLs) have been extensively mapped in human cells and tissues, but the extent by which controlled, environmental perturbation influences cis-eQTLs is unclear. We carried out large-scale induction experiments using primary human...

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Detalles Bibliográficos
Autores principales: Grundberg, Elin, Adoue, Veronique, Kwan, Tony, Ge, Bing, Duan, Qing Ling, Lam, Kevin C. L., Koka, Vonda, Kindmark, Andreas, Weiss, Scott T., Tantisira, Kelan, Mallmin, Hans, Raby, Benjamin A., Nilsson, Olle, Pastinen, Tomi
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3024267/
https://www.ncbi.nlm.nih.gov/pubmed/21283786
http://dx.doi.org/10.1371/journal.pgen.1001279